STANGYL 25 mg - Information for the patient (2023)

2. What you need to know before using Stangyl 25mgobserve?

Stangel 25mgmust not take

  • if you are allergic to trimipramine, other tricyclic antidepressants, wheat starch or any of the other ingredients of this medicine (listed in section 6)

  • in case of acute intoxication with alcohol, sleeping pills, painkillers and psychotropic drugs,

  • in acute states of confusion,

  • with untreated increased pressure in the eye (narrow-angle glaucoma),

  • urination problems such as urinary retention or an enlarged prostate (prostatic hyperplasia) with residual urine,

  • if you have recently had a heart attack

  • by narrowing of the stomach (pyloric stenosis),

  • in case of intestinal paralysis and intestinal obstruction (paralytic ileus),

  • while taking the so-called irreversibleMAO- Inhibiting.

Warnings and precautions

The following describes when you should take Stangyl 25mgmust be used only under certain conditions and with extreme caution. Please ask your doctor about this. This also applies if the information concerned you previously.

Stangel 25mgshould be used with particular caution in case of:

  • Enlargement of the prostate gland (prostatic hyperplasia) without residual urine,

  • increased readiness to have seizures (epilepsy),

  • severe liver or kidney damage

  • existing decrease in the efficiency of the hematopoietic systemLub.history of hematopoietic disorders,

  • takes the so-called "reversible".MAO-Inhibitors" (see section "Use of Stangyl 25mgtogether with other substances")

  • elderly patients, especially sensitive to sedatives and prone to hypotonia when moving from lying to standing position and chronic constipation,

  • slow heart rate (bradycardia),

  • some heart diseases (congenital QT syndrome or other clinically significant heart damage, especially circulation disorders in the coronary vessels, conduction disorders, arrhythmias),

  • Concomitant treatment with medicines that also cause ECG changes (prolongation of the QT interval), slow heart rhythm or low potassium levels in the blood (see "Use of Stangyl 25 mg/ml").mgtogether with other substances")

  • existing electrolyte disturbances (z. B.low levels of potassium or magnesium in the blood)

  • Concomitant treatment with medicines that may increase the risk of serotonin syndrome (see the section "Use of Stangyl 25 mgmgtogether with other drugs"). Serotonergic syndrome is a potentially life-threatening condition. Symptoms of serotonin syndrome may include restlessness, confusion, rapid heart rate, increased body temperature, rapid changes in blood pressure, overactive reflexes, diarrhea and coma. If you experience any of these symptoms , you must contact your doctor immediately.

If manic mood occurs, Stangyl 25mgstop and initiate appropriate treatment.

Under treatment with Stangyl 25mgAs with other tricyclic antidepressants, laboratory tests including complete blood counts and liver enzymes should be performed regularly.

Treatment with tricyclic antidepressants increases the risk of developing diabetes. Therefore, your doctor will check your blood sugar accordingly if you are diabetic or if you are at increased risk of developing diabetes.

Because trimipramine can lower the seizure threshold, aEEG-monitoring (EEG= electroencephalography, measurement of brain activity currents) is recommended (see "Tag Stangyl 25mgtogether with other substances"). If convulsions occur, treatment should be discontinued.

Under the soothing, calming effects of Stangyl 25mgusually begins immediately within the first few hours, the mood-lifting antidepressant effect can usually only be expected after 1 to 3 weeks.

If you notice increased insomnia and nervousness at the start of treatment, your doctor may increase your dose of Stangyl 25mglimited or temporary additional treatment of symptoms becomes necessary.

Suicidal thoughts and deepening depression

Depressed people may sometimes have thoughts of harming or killing themselves. These may increase when you start antidepressants as all these medicines take time to work, usually around two weeks but sometimes longer.

Such thoughts are more likely

  • if you have previously had thoughts of killing or harming yourself

  • if you are a young adult. Information from clinical trials has shown an increased risk of suicidal behavior in adults under 25 years of age with psychiatric disorders who were treated with antidepressants.

Contact your doctor or go to hospital immediatelyif you ever have thoughts of harming or killing yourself.

It may be helpful to tell a friend or relative about thisthat you are depressed. Ask them to read this leaflet. Ask them to tell you if they think your depression is getting worse or if they are concerned about changes in your behaviour.

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Sudden discontinuation of long-term treatment with high doses of Stangyl 25mgshould be avoided as withdrawal symptoms such as headache, nausea, restlessness, restlessness, sweating, nausea, vomiting and difficulty sleeping may occur (see 'If you stop taking Stangyl 25 mgmginterrupt").

children and teenagers

Stangel 25mgshould not be used to treat depression in children and adolescents under the age of 18. Tricyclic antidepressants have shown no therapeutic benefit in depression trials in this age group. Studies with other antidepressants (SSRI,SNRI) have shown an increased risk of suicide, self-injurious and hostile behavior associated with the use of these drugs. These risks may also apply to Stangyl 25mgnot excluded. Furthermore, Stangyl is 25 years oldmgis associated with risk of cardiovascular side effects in all age groups. In addition, there is a lack of long-term safety data in children and adolescents with regard to growth, maturation and intellectual and behavioral development.

heart disease and the elderly

Heart disease and the elderly should have their heart function checked regularly, as this class of medication increases the risk of rapid heartbeat, low blood pressure and quinidine-like effects.

Elderly patients with reduced metabolism, kidney, liver or heart function before and during treatment with Stangyl 25mgadequate follow-up should be performed and the dose should be adjusted accordingly. In particular, a low starting dose followed by a slow dose escalation and a low maintenance dose should be chosen (see also section 3).

Taking Stangyl 25mgtogether with other substances

Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.

Effect of alcohol and concomitant use of other central nervous system depressants, such as:

  • morphine derivatives (pain reliever, cough suppressant and substitution therapy),

  • Sleeping pills and sedatives (e.gz. B.barbiturater, benzodiazepiner),

  • sedative antihistamines (anti-allergy medicines that can make you feel tired)

  • neuroleptics (medicines to treat schizophrenia and psychosis),

  • centrally acting antihypertensives (some medicines used to treat high blood pressure,z. B.alfamethyldopa, clonidin)

  • baclofen (a medicine used to relax skeletal muscles in spinal cord injury or multiple sclerosis),

  • thalidomide (a medicine to treat multiple myeloma)

may lead to an increase in depression of the central nervous system.

Alcoholic beverages and other substances containing alcohol should be avoided during treatment with antidepressants.

Simultaneous use of baclofen can lead to a reduction in muscle tone.

With the simultaneous administration of other substances that also inhibit the effect of acetylcholine (have an anticholinergic effect), an increase in central symptoms (especially delirium) must be expected.

Stangel 25mgunwanted peripheral effects such asz. B.Urinary retention, occurrence of acute glaucoma, constipation and dry mouth after atropine-like drugs (z. B.bromek ipratropium, bromek tiotropium, chlorek trospium, butyloskopolamina).

The effectiveness of substances that directly or indirectly lead to stimulation of the sympathetic nervous system (sympathomimetic amines,z. B.adrenaline, norepinephrine, dopamine) can be reduced by simultaneous administration of Stangyl 25mgbe strengthened. This can lead to paroxysmal high blood pressure and cardiac arrhythmias.

Special attention should be paid to vasoconstrictor additives in local anesthesia. Adrenaline injected under the skin or into the gums to stop bleeding can lead to high blood pressure attacks and heart arrhythmias.

So-called irreversibleMAO- Inhibitors should be discontinued at least 14 days before starting treatment with trimipramine. Additional gift "reversibleMAO-inhibitory" (z. B.moclobemide) is possible in isolated cases if all necessary precautions are taken and the dose is slowly increased.

So-called "non-selective".MAO- inhibitor" (npz. B.Tranylcypromine) should not be taken with tricyclic antidepressants such as trimipramine due to possible effects on blood pressure.

With simultaneous or previous use of serotonin reuptake inhibitors, e.gz. B.Citalopram, fluoxetine, fluvoxamine, paroxetine and sertraline can increase blood levels of both antidepressants. Simultaneous use requires increased monitoring by the doctor and, if necessary, reduction of the dose of Stangyl 25mg Lub.serotonin reuptake inhibitor.

If you have taken fluoxetine before and are currently taking Stangyl 25mgto be treated, your doctor will start you on a lower dose than usual and increase it slowly.

Simultaneous use with other so-called administration of serotonergic active substances can lead to serotonin syndrome (see section 2 "Warnings and precautions").

Examples of such medicines are:

  • triptans (used for migraines),

  • other medicines used to treat depressionz. B.serotonin reuptake inhibitors,MAO- inhibitors or medicines containing lithium,

  • medicines containing linezolid, an antibiotic (used to treat infections)

  • medicines containing tramadol (used to treat severe pain)

  • Preparations containing L-tryptophan (used e.gz. B.for insomnia and depression)

  • Preparations containing St. John's wort (Hypericum perforatum, a natural remedy used to treat mild depression).

Buprenorphine - This medicine can be taken together with Stangyl 25mginteraction and symptoms such as involuntary, rhythmic muscle contractions, including those controlling eye movements, agitation, hallucinations, coma, excessive sweating, tremors, hyperreflexia, increased muscle tension and body temperature above 38°Csee you. Contact your doctor if any of these symptoms occur.

Stangel 25mgmay reduce the effectiveness of guanethidine-type antihypertensivesLub.Reduction of clonidine with risk of excessive increase in blood pressure (rebound hypertension) in patients treated with clonidine.

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Concomitant use of antihypertensive drugs (except clonidine and related drugs) may enhance their antihypertensive effect. There is an increased risk of a sudden drop in blood pressure when going from a lying to a standing position.

Concomitant use of medications that also cause ECG changes (QT prolongation) should be avoided (z. B.antiarrhythmic classIAor III, antibiotics, antimalarials, antihistamines, neuroleptics) leads to a decrease in the amount of potassium in the blood (hypokalemia) (z. B.certain diuretics, glucocorticoids) cause the heart to beat slowly (z. B.beta blockers, diltiazem, verapamil, clonidine, digitalis) or may inhibit the liver breakdown of trimipramine (z. irreversibleMAO-Hemmer, Imidazol-Antimykotika).

Stangel 25mgthe effectiveness of drugs for heart rhythm disorders (antiarrhythmics), especially type Ia (z. B.Quinidine) and type III (z. B.amiodarone).

In combination therapy withAntipsychotics(Medicines for the treatment of split mental disorders) plasma concentrations of the tricyclic antidepressant may be increased.

Plasma concentrations of tricyclic antidepressants may also increase during concomitant treatment with cimetidine.

The dosage of antiepileptics (antiepileptics used for people with epilepsy) may need to be adjusted, as trimipramine may lower the seizure threshold and an increased tendency to seizures may be expected. These patients should be monitored clinically.

During the administration of valproic acid, patients should be monitored clinically and, if necessary, the dose of Stangyl should be adjusted.mgset.

Simultaneous administration of carbamazepine can lead to generalized seizures (lowering of the seizure threshold with antidepressants) and to a decrease in the plasma concentration of the tricyclic antidepressant (due to increased metabolism in the liver). Patients should be monitored clinically and doses adjusted as needed.

Taking Stangyl 25mgalong with food, drinks and alcohol

Taking Stangyl 25mgshould not be taken together with black tea, as tannic acids contained in tea weaken the effect of Stangyl 25mgcan reduce. However, you do not have to completely give up black tea if you drink it at a different time than taking Stangyl.

It cannot be excluded that the consumption of coffee or fruit juice also leads to a reduced effect due to the formation of poorly soluble complexes with trimipramine, which has been shown with other antidepressants.

When using Stangyl 25mgavoid drinking alcohol if possible.

pregnancy and breastfeeding period

If you are pregnant or breast-feeding, suspect you are pregnant or are planning to become pregnant, ask your doctor for advice before taking this medicine.

Taking Stangyl 25mgnot recommended during pregnancy unless clearly necessary and only after a careful benefit/risk assessment.

If you have taken this medicine in the last stages of your pregnancy, your baby may experience adjustment problems and withdrawal symptoms such as irritability, low muscle tone, tremors, convulsions, irregular breathing, poor feeding and constipation.

Your doctor will advise you whether you should start, continue or stop breast-feeding or stop taking this medicine. She will consider the benefits of breastfeeding for your baby and the benefits of therapy for you.

Ability to drive and operate machinery

There is a potential hazard when driving or operating machinery due to impaired alertness. fixed 25mgmay cause blurred vision and drowsiness. Even when used as intended, responsiveness may change to such an extent thatz. B.the ability to drive and operate machinery is reduced. You can no longer react quickly and specifically enough to unexpected and sudden events.

Stangel 25mgcontains gluten.

This medicine contains very small amounts of gluten (from wheat starch) and if you have celiac disease it is very unlikely to cause problems.

One tablet contains no more than 261 micrograms of gluten.

If you are allergic to wheat (not the same as celiac disease), do not take this medicine.

3. How does Stangyl 25 perform?mgto take?

Always use this medicine exactly as your doctor has told you. Ask your doctor or pharmacist if you are in doubt.


Unless your doctor tells you otherwise, the usual dose is:

The effective dose is reached gradually, starting with1-2Tabletten Stangyl 25mg(25-50 mgtrimipramine) daily, then slowly increase the dose if necessary. In moderate depressive states the daily dose is4-6Tabletten Stangyl 25mg(100-150 mgtrimipramine).

It can be taken during the day (morning, noon, evening) or as a single dose in the evening. Especially in cases of insomnia, it should be taken in the evening in a single dose.

Stangel 25mgshould not be used to treat depression in children and adolescents under the age of 18 (see also section 2 "Children and adolescents").

Elderly and debilitated patients with hypertension, low blood pressure and arteriosclerosis should take only moderate doses orally at longer intervals. The dose should be carefully adjusted in patients with liver or kidney insufficiency (failure).

application type

Stangel 25mg, tablets, swallowed whole with liquid, during or after a meal.

The tablets can be divided into equal doses.

period of use

From clinical experience, treatment with Stangyl 25mgfor a period of approx4-6weeks are necessary to achieve effective therapy with lasting mood normalization.

To prevent relapse to the depressive phase, maintenance treatment with trimipramine is recommended for several months - 4 to 9 months - after the first depressive phase with the dose used in the acute phase throughout the phaseLub.partial improvement. In patients with a history of several depressive phases, it may be necessary to continue treatment for several years at the dose that led to improvement in the current phase.

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If you take a higher dose of Stangyl 25mgyou took than you should

While taking Stangyl 25mgin a higher dose than that indicated in the package insert, various degrees of dysfunction of the body may occur. The higher the dose, the greater the risk to the patient. Overdose can be fatal. Therefore increased intake of Stangyl 25mgrespond.

These dysfunctions in the body are manifested at the beginning of an increased need for sleep and even decreased consciousnessLub.Coma at high doses, in cardiovascular disorders up to cardiac arrest and convulsions. Cardiovascular disorders can be particularly dangerous for the patient, especially if the heart has already been damaged. Symptoms of poisoning can appear much earlier in childrenOkay.2mgTrimipramine prokgbody weight.

If you accidentally take more than the prescribed dose, contact your doctor. Depending on the dose takenLub.Based on the symptoms, the doctor decides on further treatment.

In the case of children, you must always consult a doctor - even if the intake is small.

It must be remembered that even with a slight overdose, the ability to react is always more reduced than with a normal dose.

When taking other medications, especially other psychotropic medications, the above-mentioned physical disorders may occur even at lower doses than indicated (see also the section "Using Stangyl 25 mg/ml").mgtogether with other substances").

Notes for the attending physician

Treatment should include symptomatic treatment and monitoring of vital signs, especially cardiac and respiratory function, for at least three to five days.

As an antidote, the use of physostigmine salicylate 2mgslowI. adults, in children0,5–1 mg I. w.In case of pronounced hypotension or shock, the appropriate amount should be supplemented.No adrenaline!

If you stop taking Stangyl 25mgI forgot

The next dose of Stangyl is the 25thmgtaken in the prescribed dose. increase the dose,z. B.Do not take a double dose after forgetting a single dose.

If you stop taking Stangyl 25mginterrupt

In this case, the symptoms of depressive illness (z. B.sleep disorders, depression). That is why Stangyl 25 therapymgdon't finish early. As with initiation of treatment, weaning should be done gradually, as directed by your doctor, with a gradual reduction of the daily dose. With abrupt discontinuation, especially after prolonged use, withdrawal phenomena such as e.gz. B.There is discomfort, nausea, headache, sleep disturbances, anxiety, restlessness, increased irritability.

Ask the doctor or pharmacist if you have any further questions about the use of this medicine.

4. What side effects are possible?

Like all medicines, this medicine can cause side effects, although not everybody gets them.

The frequency of side effects is listed as "not known" because it cannot be estimated from the available data.

blood diseases

Some changes in blood counts (z. B.leukopenia, agranulocytosis, thrombocytopenia and eosinophilia). As with other tricyclic antidepressants, regular blood counts should therefore be monitored during treatment with trimipramine.

endocrine disorders

Increased water intake in the body (insufficientADHsecretion), a drop in blood sugar below normal (hypoglycaemia).

Similar to related drugs: increase in prolactin in the blood and/or discharge from the breast (galactorrhoea).

Metabolic and nutritional disorders

Increased blood sugar levels, increased risk of developing diabetes (see section 2 "Warnings and precautions").

Mental disorders

Anxiety, sleep disturbances, mood swings, confusion in elderly patients, disturbance of consciousness (delirium syndromes).

Turning depression into hypomania or mania.

Cases of suicidal thoughts and behavior during Stangyl therapy 25mgor shortly after treatment (see section 2 "Warnings and precautions").

disorders of the nervous system

Especially at the beginning of treatment: tremor, drowsiness, dizziness.

Speech disorders, abnormal sensations (usually on the skin,z. B.tingling), peripheral nerve diseases (polyneuropathy), drowsiness, convulsions and extrapyramidal disorders such as restlessness, gait disturbances, motor dysfunctions.

eye disorders

Especially at the beginning of treatment: blurred vision.

ear disorders

ringing in the ears (tinnitus).

Cardiovascular disorders

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Especially at the beginning of treatment: orthostatic hypotension (impaired circulatory control with a drop in blood pressure), short-term loss of consciousness (syncope), increased heart rate.

lower blood pressure. Certain ECG changes (prolongation of the QT interval), potentially life-threatening "torsades de pointes". In such cases, treatment with Stangyl 25mgcancel.

Cardiac arrhythmias and conduction disorders (especially in case of overdose or existing diseases of the cardiovascular system).

vascular diseases

hot flashes.

Respiratory and chest disorders

Allergic lung reactions in the form of a certain type of pneumonia (interstitial pneumonitis,z. B.eosinophil lung infiltrate) or pleurisy.

Gastrointestinal disorders

Especially at the beginning of treatment: dry mouth, constipation, indigestion and nausea.

Liver and biliary disorders

As an expression of hypersensitivity: hepatobiliary reactions, usually manifested by transient increases in liver enzymes and serum bilirubin in the form of cytolytic or cholestatic hepatitis (hepatitis,you. case of biliary stagnation).

Regular laboratory tests with determination of liver enzymes should be carried out.

skin disorders

redness of the skin With the right disposition: Signs of an allergic event, especially of the skin. hair loss

bone disorders

An increased risk of bone fractures has been observed in patients treated with this class of drugs.

Kidney and urinary tract disorders

Difficulty urinating, urinary retention.

Diseases of the genitals and the mammary gland

Breast enlargement (macromastia).

Sexual dysfunctions.

General ailments

Especially at the beginning of the treatment: fatigue.

weight gain, sweating.

Wheat starch can cause hypersensitivity reactions.

What countermeasures should be taken in case of side effects?

To minimize possible side effects, a creeping dose should be used as described in the dosage instructions.

If you experience serious side effects (z. B.agranulocytosis, convulsions, thrombocytopenia) is Stangyl 25 treatmentmgshould be discontinued immediately and appropriate symptomatic treatment initiated.

In case of allergic reactions, you must consult your doctor before further use, who will decide on the further treatment.

Reporting of side effects

If you experience any side effects, talk to your doctor or pharmacist. This includes all side effects not mentioned in this leaflet. You can also directly discuss the side effects

Federal Institute for Pharmaceuticals and Medical Products

ca.Drug monitoring

Kurt-Georg-Kiesinger-Allee 3



sue. By reporting side effects, you can help provide more information about the safety of this medication.

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What is sertraline 25 mg used for? ›

Sertraline is used to treat depression, obsessive-compulsive disorder (bothersome thoughts that won't go away and the need to perform certain actions over and over), panic attacks (sudden, unexpected attacks of extreme fear and worry about these attacks), posttraumatic stress disorder (disturbing psychological symptoms ...

Does trimipramine help with anxiety? ›

In addition to being an antidepressant, Trimipramine is also an anxiolytic which implies that it helps overcome anxiety. Furthermore, it also helps the patient overcome insomnia or sleep disorders.

Is trimipramine a sedative? ›

General information. Trimipramine is a sedating tricyclic antidepressant that has been used as a hypnotic [1]; it shares this activity with other drugs of its class, notably amitriptyline, dosulepin, doxepin, and trazodone, and with the tetracyclics mianserin and mirtazapine.

Does Surmontil help sleep? ›

Surmontil (trimipramine), a tricyclic antidepressant, is used to treat depression. It also has some sedative properties. It is said to “brighten up” the dreams because it does not affect the rapid eye movement (REM) phase of sleep.

What are the side effects of 25 mg of sertraline? ›

Nausea, dizziness, drowsiness, dry mouth, loss of appetite, increased sweating, diarrhea, upset stomach, or trouble sleeping may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

What is the most common side effect of sertraline? ›

The most common side effect of sertraline in clinical trials was nausea. About 1 in 4 people taking sertraline experience it. It's most likely to occur when you first start sertraline or right after a dose increase. Luckily, nausea with sertraline doesn't tend to last.

What is the number 1 drug for anxiety? ›

Benzodiazepines (also known as tranquilizers) are the most widely prescribed type of medication for anxiety. Drugs such as Xanax (alprazolam), Klonopin (clonazepam), Valium (diazepam), and Ativan (lorazepam) work quickly, typically bringing relief within 30 minutes to an hour.

What is the very best medication for anxiety? ›

SSRIs and SNRIs are often the first-line treatment for anxiety. Common SSRI brands are Celexa, Lexapro, Luvox, Paxil, and Zoloft. Common SNRI brands are Pristiq, Cymbalta, and Effexor XR. Pros: They are effective for a lot of people and they have a solid safety profile.

What is a calming pill for anxiety? ›

Benzodiazepines most commonly used to treat anxiety disorders are clonazepam (Rivotril)*, alprazolam (Xanax) and lorazepam (Ativan). Also used are bromazepam (Lectopam), oxazepam (Serax), chlordiazepoxide (once marketed as Librium), clorazepate (Tranxene) and diazepam (Valium).

What are the warnings for trimipramine? ›

Trimipramine may make your skin sensitive to sunlight. you should know that trimipramine may cause angle-closure glaucoma (a condition where the fluid is suddenly blocked and unable to flow out of the eye causing a quick, severe increase in eye pressure which may lead to a loss of vision).

What is the side effect of trimipramine? ›

Dizziness, drowsiness, difficulty urinating, headache, weakness, changes in appetite/weight, dry mouth, blurred vision, and constipation may occur. If any of these effects last or get worse, notify your doctor or pharmacist promptly.

What are the side effects of trimipramine on the heart? ›

Trimipramine may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can rarely cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that need medical attention right away.

What are the most common side effects of Surmontil? ›

Dizziness, drowsiness, difficulty urinating, headache, weakness, changes in appetite/weight, dry mouth, blurred vision, and constipation may occur. If any of these effects last or get worse, notify your doctor or pharmacist promptly.

Is trimipramine addictive? ›

If you've been taking trimipramine for a while and want to stop taking it, talk to your provider first. While it's not addictive, stopping trimipramine suddenly can cause nausea, headache, and uneasiness for a few days until your body readjusts.

Does trimipramine cause constipation? ›

See your eye doctor if the problem does not go away or is severe. This medication can cause constipation.

What foods to avoid when taking sertraline? ›

Is there any food or drink I need to avoid? Do not drink grapefruit juice while you're taking this medicine. Grapefruit juice can increase the amount of sertraline in your body and increase the risk of side effects.

What is the best time of day to take sertraline 25 mg? ›

Take sertraline once a day. You can take it with or without food. You can choose to take sertraline at any time, as long as you stick to the same time every day. If you have trouble sleeping, it's best to take it in the morning.

How long does it take for 25 mg sertraline to work? ›

Zoloft (sertraline), a common selective serotonin reuptake inhibitor (SSRI) antidepressant, can take about 4 to 6 weeks of regular dosing to reach its full therapeutic effect for depression. The initial effects may begin within the first 1 to 2 weeks of treatment.

What are the scary side effects of sertraline? ›

Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea. Sertraline can affect growth in children.

How bad can sertraline make you feel? ›

Sertraline can make you feel very restless in the first few weeks that you take it and may affect you when you sit or stand still. It can also disturb your sleep, and your eyesight. You should talk to your doctor about any future exams if you are starting sertraline.

Is sertraline a high risk medication? ›

There is a bleeding risk associated with sertraline, as it may inhibit platelet aggregation. Sertraline, like other antidepressants, may increase the risk of suicidal ideation and behavior in children, adolescents, and young adults with major depression.

What is the best anti anxiety medication for elderly? ›

Buspirone is an anti-anxiety drug that has been shown to be effective for older adults. Benzodiazepines, another anti-anxiety drug, are effective but should be prescribed carefully to older adults because of risk of memory impairment, unsteadiness, and falls.

What is the new treatment for anxiety? ›

The FDA has approved a phase 2b study of an optimized form of LSD for the treatment of anxiety. The drug, called MM-120, is being developed by MindMed and is intended to treat generalized anxiety disorders and other mental conditions. MindMed is expected to begin clinical trials in 2022.

What's the best drug for anxiety and depression? ›

Medications for anxiety and depression
  • fluoxetine (Prozac)
  • sertraline (Zoloft)
  • paroxetine (Paxil)
  • fluvoxamine (Luvox)
  • citalopram (Celexa)
  • escitalopram (Lexapro)
Aug 30, 2022

Is anxiety a form of mental illness? ›

Anxiety disorders are the most common of mental disorders and affect nearly 30% of adults at some point in their lives. But anxiety disorders are treatable and a number of effective treatments are available. Treatment helps most people lead normal productive lives.

What is the new medication for anxiety in 2023? ›

A second therapeutic candidate, LYT-310 (oral cannabidiol), is expected to enter the clinic in Q4 of 2023. A second therapeutic candidate, LYT-310 (oral cannabidiol), is expected to enter the clinic in Q4 of 2023.

Is there a supplement for anxiety? ›

Research suggests that certain dietary supplements may help reduce anxiety symptoms, including magnesium, vitamin D, saffron, omega-3s, chamomile, L-theanine, vitamin C, curcumin, CBD, and multivitamins.

What medication is used for racing thoughts? ›

Antipsychotics are commonly prescribed to help with symptoms such as hallucinations, delusions, or racing thoughts, but can also be prescribed for individuals without those symptoms. Some antipsychotics are considered mood stabilizers because they, too, even out the highs and lows.

How does sertraline 25mg make you feel? ›

How will it make me feel? Antidepressants like sertraline help to improve your mood so you feel better. You may notice that you sleep better and get on with people more easily because you're less anxious. You'll hopefully be more relaxed about things that used to worry you.

Does 25mg of sertraline make a difference? ›

Therapy should be initiated at 25 mg/day. After 1 week, the dose should be increased to 50 mg once daily. This dosage regimen has been shown to reduce the frequency of early treatment emergent side effects characteristic of panic disorder. Patients not responding to a 50 mg dose may benefit from dose increases.

When is the best time to take sertraline 25 mg? ›

Take sertraline once a day. You can take it with or without food. You can choose to take sertraline at any time, as long as you stick to the same time every day. If you have trouble sleeping, it's best to take it in the morning.

Why is it best to take sertraline at night? ›

You can take it either in the morning or evening, depending on your lifestyle and any side effects you experience. For example, if sertraline makes you drowsy, taking it at night might be your best choice. It's important that you establish a set time to take this medication every day and follow that schedule.

Do you feel better immediately on sertraline? ›

Can Zoloft work immediately? Zoloft will not work immediately however, it can have a positive positive effect on a patient's energy level, sleep and appetite within the first 1-2 weeks.

How do I know sertraline is working? ›

“Your sertraline is working if you feel calmer. Your negative moods or anxiety will not be as intense. You should be enjoying activities more. And your sleeping and eating habits should be more stable,” says Doughty.

What are the negative effects of sertraline? ›

Common side effects
  • Feeling sick (nausea) Try taking sertraline with or after food. ...
  • Headaches. Make sure you rest and drink plenty of fluids. ...
  • Being unable to sleep. Take sertraline first thing in the morning.
  • Feeling sleepy. ...
  • Diarrhoea. ...
  • Dry mouth. ...
  • Feeling dizzy. ...
  • Feeling tired or weak.

How long does it take for sertraline to kick in? ›

Antidepressants like sertraline can start to work on depression within the first two weeks of treatment, and the improvement continues over the following few weeks. It may take four weeks or longer for you to get the full effect. For anxiety, antidepressants like sertraline can take slightly longer to work.

Can 25mg of sertraline help anxiety? ›

For panic disorder, posttraumatic stress disorder, or social anxiety disorder: Adults—At first, 25 milligrams (mg) once a day, taken either in the morning or evening. Your doctor may adjust your dose as needed. However, the dose is usually not more than 200 mg per day.

What are the benefits of taking sertraline? ›

Sertraline works by increasing the levels of a mood-enhancing chemical called serotonin in your brain. It helps many people recover from depression, and has fewer unwanted side effects than older antidepressants. Sertraline comes as tablets, which are available only on prescription.

Will I gain weight on sertraline? ›

Antipsychotic drugs, antidepressants , and mood stabilizers are common drugs that have the most potential to increase weight gain. All 12 of the leading antidepressants, including fluoxetine (Prozac), sertraline (Zoloft), and escitalopram (Lexapro), make gaining weight more likely.

How safe is sertraline? ›

Are There Any Risks For Taking Sertraline For Long Periods Of Time? To date, there are no known problems associated with long term use of sertraline. It is a safe and effective medication when used as directed.

Is it hard to sleep on sertraline? ›

Yes, insomnia is one of the most common side effects of the medication Zoloft. Zoloft is the brand name for the antidepressant sertraline. However, this is one of the side effects that will most likely improve after a few weeks of taking the medication.

Do you struggle to sleep on sertraline? ›

Insomnia and a general reduction in sleep quality are both common side effects of SSRIs and other antidepressants. People who use sertraline may find that they now have trouble sleeping, or find themselves waking up frequently throughout the night. Sertraline can also cause you to be more sleepy than usual.

What are the side effects of sertraline in the first week? ›

Common side effects during the first week or two of taking Zoloft include nausea, headache, fatigue, and constipation. These side effects should go away once your body gets used to the medication. If you continue to have side effects after a few weeks or experience any serious side effects, call your doctor or 911.

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